Guadagnino is a surname. Notable people with the surname include: Kathy Guadagnino (born 1961), American golfer. Luca Guadagnino (born 1971), Italian director and screenwriter. Vinny Guadagnino (born 1987), American Jersey Shore star and actor. See also. Guadagnini (surname) https://en.wikipedia.org/wiki/Guadagnino