S9 E11 | Vital But Often Overlooked Factors In Recurrent Miscarriage and Pregnancy Loss

S9 E11 | Vital But Often Overlooked Factors In Recurrent Miscarriage and Pregnancy Loss

The Worst Girl Gang Ever · 2025-06-22

In this deeply insightful episode of The Worst Girl Gang Ever, we welcome back Dr. Sami, Fertility Consultant at Plan Your Baby, to unpack a vital but often overlooked factor in recurrent miscarriage and pregnancy loss: blood clotting disorders, also known as thrombophilias.

Dr. Sami explains:



What inherited and acquired clotting disorders are




How conditions like Factor V Leiden, Prothrombin mutations, and Antiphospholipid Syndrome (APS) dramatically increase the risk of miscarriage




Why APS is one of the most treatable causes of miscarriage with aspirin and heparin therapy




The shocking statistic: with proper treatment, miscarriage rates can drop from 80% to just 20%




Why many women are told "everything is normal"—and why that may be far from the truth




What you can and should ask for if you’ve had two or more miscarriages




The difference in treatment approaches between NHS vs private fertility care




In this episode, we discuss:



Recurrent miscarriage causes and treatments




Blood clotting and pregnancy loss




APS and miscarriage




Factor V Leiden miscarriage risk




Miscarriage and low-dose aspirin




Heparin in pregnancy




Fertility consultant insights




Blood thinning medication in pregnancy




Safe treatments for preventing miscarriage




Plan Your Baby fertility support




Whether you’ve been through pregnancy loss or are supporting someone who has, this episode offers hope, science, and practical steps toward your next healthy pregnancy.



About The Worst Girl Gang Ever

The Worst Girl Gang Ever is a real, honest, and emotive podcast that covers the heartbreaking subject of miscarriage, infertility, and baby loss. Expect raw conversations about unspoken experiences, hosted by TWGGE founders Bex Gunn and Laura Buckingham. This show aims to break the silence and open dialogue around miscarriage and pregnancy loss. No more shame, no more taboo—let’s change the narrative for future generations.

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We are here to tell you that you are entitled to grieve, and that your grief is not disproportionate to your loss. We are here to oxapen up the dialogue around miscarriage, so we don’t perpetuate the shame, judgement and isolation so many of us feel following pregnancy loss. We are here to equip you with knowledge, tools and guidance to support and help you in whatever way you need.

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The Worst Girl Gang Ever

The Worst Girl Gang Ever is a real, honest emotive podcast that covers the heartbreaking subject of miscarriage, infertility and baby loss, expect honest conversations about unspoken experiences. Hosted by TWGGE founders Bex Gunn and Laura Buckingham, this show is a chance to break the silence and really open up the dialogue around the topic of miscarriage and pregnancy loss. No more shame, no more taboo - let's ditch that for our children; the ones that will come, the ones that are and the ones that never came to be..

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