Exploring the Limitations and Potentials of RCTs: Beyond the Gold Standard
Are Randomised Controlled Trials (RCTs) always the definitive 'gold standard' in research? In the latest episode of In Silico Trials, Real Impacts!, we explore the nuanced landscape of RCTs, questioning their universal applicability and examining the complexities they often obscure. While RCTs are celebrated for their rigour, this discussion delves into their limitations, particularly when findings are applied across diverse contexts.
Drawing on seminal work by Deaton and Cartwright (2018), this episode highlights the critical role that RCTs play in the medical and social sciences, while underscoring the importance of complementing them with observational studies and theoretical frameworks. Ethical considerations and the need for a more integrated approach to research take centre stage, offering a fresh perspective on evidence generation.
Whether you're a researcher, healthcare professional, or simply curious about scientific methodologies, this episode provides thought-provoking insights into the evolving landscape of research.
Source: Deaton A, Cartwright N. Understanding and misunderstanding randomized controlled trials. Soc Sci Med. 2018 Aug;210:2-21.
In Silico Trials, Real Impacts!
𝗜𝗻 𝗦𝗶𝗹𝗶𝗰𝗼 𝗠𝗲𝗱𝗶𝗰𝗶𝗻𝗲 𝗥𝗲𝘃𝗼𝗹𝘂𝘁𝗶𝗼𝗻: 𝗨𝗞 𝗖𝗘𝗶𝗥𝗦𝗜’𝘀 𝗢𝗳𝗳𝗶𝗰𝗶𝗮𝗹 𝗣𝗼𝗱𝗰𝗮𝘀𝘁 on 𝗩𝗶𝗿𝘁𝘂𝗮𝗹 𝗖𝗹𝗶𝗻𝗶𝗰𝗮𝗹 𝗧𝗿𝗶𝗮𝗹𝘀 & 𝗛𝗲𝗮𝗹𝘁𝗵𝗰𝗮𝗿𝗲 𝗜𝗻𝗻𝗼𝘃𝗮𝘁𝗶𝗼𝗻
Welcome to the official podcast of the 𝗨𝗞 𝗖𝗲𝗻𝘁𝗿𝗲 𝗼𝗳 𝗘𝘅𝗰𝗲𝗹𝗹𝗲𝗻𝗰𝗲 𝗼𝗻 𝗜𝗻 𝗦𝗶𝗹𝗶𝗰𝗼 𝗥𝗲𝗴𝘂𝗹𝗮𝘁𝗼𝗿𝘆 𝗦𝗰𝗶𝗲𝗻𝗰𝗲 𝗮𝗻𝗱 𝗜𝗻𝗻𝗼𝘃𝗮𝘁𝗶𝗼𝗻 (𝗨𝗞 𝗖𝗘𝗶𝗥𝗦𝗜) and the 𝗜𝗻𝗦𝗶𝗹𝗶𝗰𝗼𝗨𝗞 𝗣𝗿𝗼 𝗜𝗻𝗻𝗼𝘃𝗮𝘁𝗶𝗼𝗻 𝗥𝗲𝗴𝘂𝗹𝗮𝘁𝗶𝗼𝗻𝘀 𝗡𝗲𝘁𝘄𝗼𝗿𝗸.
Discover how 𝗰𝗼𝗺𝗽𝘂𝘁𝗮𝘁𝗶𝗼𝗻𝗮𝗹 𝗺𝗼𝗱𝗲𝗹𝗹𝗶𝗻𝗴 and 𝘃𝗶𝗿𝘁𝘂𝗮𝗹 𝗰𝗹𝗶𝗻𝗶𝗰𝗮𝗹 𝘁𝗿𝗶𝗮𝗹𝘀 are transforming healthcare:
🔬 𝗗𝗶𝗴𝗶𝘁𝗮𝗹 𝗛𝗲𝗮𝗹𝘁𝗵 𝗜𝗻𝗻𝗼𝘃𝗮𝘁𝗶𝗼𝗻: Explore breakthrough virtual testing methods for medical devices and pharmaceuticals
🏥 𝗛𝗲𝗮𝗹𝘁𝗵𝗰𝗮𝗿𝗲 𝗧𝗲𝗰𝗵𝗻𝗼𝗹𝗼𝗴𝘆: Learn about 𝗶𝗻 𝘀𝗶𝗹𝗶𝗰𝗼 evidence revolutionising patient care
💻 𝗖𝗼𝗺𝗽𝘂𝘁𝗮𝘁𝗶𝗼𝗻𝗮𝗹 𝗠𝗲𝗱𝗶𝗰𝗶𝗻𝗲: Understand how 𝗱𝗶𝗴𝗶𝘁𝗮𝗹 𝘁𝘄𝗶𝗻𝘀 and computer simulations accelerate drug development
🤝 𝗥𝗲𝗴𝘂𝗹𝗮𝘁𝗼𝗿𝘆 𝗜𝗻𝗻𝗼𝘃𝗮𝘁𝗶𝗼𝗻: Join experts discussing streamlined approval processes for medical innovations
📈 𝗛𝗲𝗮𝗹𝘁𝗵𝗰𝗮𝗿𝗲 𝗘𝗰𝗼𝗻𝗼𝗺𝗶𝗰𝘀: Explore cost-effective solutions driving medical advancement
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