Autism and Adaptive Responses, and exploring the mPFC, ACC, and Insula
In this episode, we explore three regions associated with social awareness- the medial Prefrontal Cortex, the Anterior Cingulate Cortex, and the Insula. We review the functions of each, the interactions between each region, and the inputs and bi-directional connections to some crucial areas of the brain. In large part, we will review adaptive responses and cover some scientific literature on these regions and the implications to Autism.
https://molecularautism.biomedcentral.com/articles/10.1186/s13229-024-00593-6
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9354837/
https://www.nature.com/articles/s42003-024-06016-9
https://www.sciencedirect.com/science/article/pii/S0149763409000815?via%3Dihub#aep-section-id15
https://www.tandfonline.com/doi/full/10.1080/17470919.2023.2242095
https://www.sciencedirect.com/science/article/abs/pii/S0006322308011578
(0:00) Intro; mPFC, ACC, and Insula
(3:26) mPFC, Excitation / Inhibition; CNTNAP2, SHANK3, Neuroligin, and PTEN
(7:42) Functions of mPFC and a primary dive into Adaptive Responses; Neuromodulators
(13:52) ACC
(15:23) the mPFC and ACC lead the way
(19:29) Scientific Studies on Theory of Mind Task and Sensory Processing
(21:52) Insula
(26:49) Scientific Study: Eye Gaze, Social Attention, Social Cognition, Observational Learning
(30:11) Social and Nonsocial Studies- different areas for Autistics versus Non-Autistic
(32:38) A study using 6-week-old Infants, attentional biases and sensorimotor and different brain areas
(35:05) Wrap Up
email: [email protected]
From the Spectrum: Finding Superpowers with Autism
I'm Ryan, and I have Autism. From the Spectrum is a podcast about Autism. I am on a mission to explain a likely cause of Autism. Autism suddenly shows up in human evolution, and it seems to be a biological adaption (neuroplasticity) to an environmental change used by living organisms for life- light. Maybe, people fail to understand how living organisms use the energy from light to drive biochemistry. In addition, I want to explain Autism. I use various scientific literature, personal experiences, and opinion. With opinion, I will explain why I feel the way I do, and give examples. I will provide links to various references for each episode. For each episode, we will discuss various aspects of Autism.
Lastly, thank you for listening to From the Spectrum podcast.
X: https://twitter.com/rps47586
Hopp: https://www.hopp.bio/fromthespectrum
email: [email protected]
- No. of episodes: 66
- Latest episode: 2025-04-21
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